Gastric tissue samples were studied using mid-IR fiber-optic attenuated total reflectance (ATR) spectroscopy. FTIR spectra of 90 tissue samples from 48 patients, including 32 normal and 58 malignant tissue samples, were chosen as examples. Malignancy was usually characterized by the absence of CH and C=O bands, a weak amide II band near 1545 cm-1, a shift of the amide I band to lower wave number, a decrease in the ～1450 cm-1 peak to less than the～1400 cm-1 peak. Subtraction spectra indicate that the amide I and amide II bands of normal and malignant tissues have larger differences in peak positions and relative intensities. The statistical analysis results confirm this conclusion. The results indicate that FTIR fiber optic techniques provide important information about cancerous tissue of the stomach, which can be used to differentiate the malignant tissue from the normal tissue. Based on the above results we successfully realize the detection of the tumor tissues of digestive tract in vivo and in situ. And the results of detection cancer near operating room and in vivo and in situ in the operating room are consistent with the conclusions for the samples stored in liquid N2, which is the basis for the clinical application.
XU Yizhuang1, YANG Limin1, XU Zhi3, ZHAO Ying2, LING Xiaofeng3, LI Qingbo1, WANG Jiansheng4, ZHANG Nengwei3, ZHANG Yuanfu1 & WU Jinguang1 1. The State Key Laboratory of Rare Earth Materials and Applications, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China
The coprecipitate Tb 0.5 Eu 0.5 3phen was synthesized. By doping the rare earth complex into polymer PVK, the EL device was fabricated with the structure of ITO/PVK∶RE/PBD/Al. Compared with the device using PVK/Eu(asprin) 3phen blend as the light emitting layer, the emission of Eu 3+ in the PVK/Tb 0.5 Eu 0.5 (asprin) 3 phen blend is greatly enhanced along with the quenching of the emission of PVK.
