Histopathological examination is still the gold standard for diagnoses of oral-maxillofacial lesions,but it is invasive and time-consuming.Optical coherence tomography(OCT)provides a kind of noninvasive,label-free,real-time and high-resolution imaging technology.In this study,in order to assess the feasibility of OCT in oral clinical application,fresh excised tissue specimens from 59 patients undergoing oral-maxillofacial surgery were imaged in detail by using a benchtop sweptsource OCT system.It is shown that different lesions or tissues can be obviously distinguished based on their different microstructural features in OCT images,and the features are similar to those of their corresponding histopathological images.It is proven that OCT has great feasibility and potential as a diagnostic aid for surgeons in oral medicine.
Optical lenses used in high temperature environment are usually affected by thermal lenses problems, but it is difficult to evaluate their focal shifts in practical applications. A three-dimensional single-lens model based on finite element solver was built to evaluate the focal shift in this study, when the temperature of surface was raised from the initial temperature to the specified temperature. An experimental method based on a Hartmann-Shack wavefront sensor was proposed to verify the rationality of the model. The nearly same results between simulations and experiments for N-BK7 and fused silica were obtained, which proves that it is feasible to analyze focal shifts of optical lenses by simulation methods.
The thermal lens problem of optical system caused by high temperature environment is a common problem. Athermal design of lenses based on optical calculation software is an effective passive compensation method. But it is difficult to determine its accuracy and measure it experimentally. We describe an athermal design technology and propose a simulated scheme to verify the accuracy of this design. Three materials with negative dn/dT have been selected to compensate for the thermal lenses produced by a fused silica lens. The results show that the compensation effect of N-PSK53A is the best.
