<正>Benzofuran-2(3H)-ones are a naturally-occurring and biologically interesting class of heterocycles. In 1997...
WANG, Chen-Ying CHEN, Jing-Bo JI, Yan-Hua LIU, Ji-Kai ZHANG, Hong-Bin (State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204) (School of Pharmacy, Center for Advanced Studies of Medicinal and Organic Chemistry, Yunnan University, Kunming 650091)
A diastereoselective method for the synthesis of chiral pyrrolidine and piperidine ring containing compounds was described. The protocol of bromination followed by aminocyclization furnishes an easily handled while highly efficient procedure for the intramolecular amidation of an isolated double bond. High diastereomeric excess was observed in this synthetic procedure.