您的位置: 专家智库 > >

国家自然科学基金(81000453)

作品数:1 被引量:0H指数:0
发文基金:国家自然科学基金高等学校学科创新引智计划更多>>
相关领域:生物学一般工业技术金属学及工艺更多>>

文献类型

  • 1篇中文期刊文章

领域

  • 1篇生物学
  • 1篇金属学及工艺
  • 1篇一般工业技术

主题

  • 1篇ADVANC...
  • 1篇CELL
  • 1篇ES
  • 1篇MECHAN...
  • 1篇BIOMEC...
  • 1篇AGGREG...

传媒

  • 1篇Acta M...

年份

  • 1篇2012
1 条 记 录,以下是 1-1
排序方式:
ADVANCES IN EXPERIMENTAL APPROACHES FOR INVESTIGATING CELL AGGREGATE MECHANICS
2012年
Cells tend to form hierarchy structures in native tissues. Formation of cell aggregates in vitro such as cancer spheroids and embryonic bodies provides a unique means to study the mechanical properties and biological behaviors/functions of their counterparts in vivo. In this paper, we review state-of-the-art experimental approaches to assess the mechanical properties and mechanically-induced responses of cell aggregates in vitro. These approaches are classified into five categories according to loading modality, including micropipette aspiration, centrifugation, compression loading, substrate distention, and fluid shear loading. We discussed the advantages and disadvantages of each approach, and the potential biomedical applications. Understanding of the mechanical behavior of cell aggregates provides insights to physical interactions between cells and integrity of biological functions, which may enable mechanical intervention for diseases such as atheromatosis and cancer.
Wenjun ZhangShuqi WangMin LinYulong HailGuiping ZhaoTian Jian LuFeng Xu
关键词:BIOMECHANICS
共1页<1>
聚类工具0