Using4-[(1-naphthylamino)phenylmethylene]-5-methyl-2-phenyl-2H-pyrazol-3(4H)one(L),its Co (Ⅱ) complex was synthesized and characterized by IR and UV in which the ligand as a-1valence bidentate with Co (Ⅱ) form2∶1complex.X-ray structure analysis indicates that the Co (Ⅱ) ion is coordinated with oxygen atoms of pyrazolinon,nitrogen atoms of imine and oxygen atoms of DMF molecules to form a distorted six-coordination octahedron.π - π reciprocity and aromatic stack interaction are observed.There are no intra-and inter-hydrogen bond in the crys-tal and the complexes are held together by electronic and Van der Waals forces.
Four hydroxamic acid derivaties were prepared by reaction of hydroxylamine hydrochloride with dimethylphthalate, dimethylisophthalate, dimethylterephthalate and dimethylsebacate respectively and characterized by IR and elemental analysis. The antibacterial activities to Escherichia coli and Staphylococcus aureus of phthaloyl, isophthaloyl, terephthaloyl and sebacoyl hydroxamic acids have been determined using paper disc method. The result indicates that their antibacterial activities to Escherichia coli are better than that to Staphylococcus aureus and among them the sebacoyl hydroxamic acid is the best one. No linear correlation was observed between the antibacterial activities and the concentration of the compounds, each has its optimum antibacterial concentration.
