Anal fistula is one of the three greatest anorectal diseases with a high prevalence. The traditional treatments(e.g., surgery) for fistula have limitations due to damage to the internal anal sphincter of patients. With recent advances in biomaterials, treatments based on biomaterial filling (e.g., scleraprotein injection, fistula plug) have emerged as novel therapies for fistula. The anal fistula plug (e.g., based on small intestinal submucosa (SIS)) has attracted increasing attention because of short term healing rate and biocompatibility. However, challenges remain for this method such as plug falling as observed in clinics. To address this, this paper analyzes the case of SIS falling under physiological condition from mechanical point of view using ANSYS simulation. It then proposes three new geometrical structures for fistula plug and compares their mechanical behavior (e.g., axial stress, reaction of constraint) with that of clinically used structure (cone shape). Based on the simulation, it optimizes the geometric parameters of fistula plug. The approach developed here can help to improve the design of fistula plug for better clinical treatments.
Shunli YangBin JiangFeng XuMin LinGuiping ZhaoTianjian Lu
The natural convective heat transfer performance and thermo-fluidic characteristics of honeycombs with/without chimney extensions are numerically investigated.The present numerical simulations are validated by the purposely-designed experimental measurements on honeycombs with/without chimney.Good agreement between numerical simulation and experimental measurement is obtained.The influences of inclination angle and geometric parameters such as cell shape,streamwise and spanwise length are also numerically quantified.With the increment in inclination angle,the overall heat transfer rate decreases for the honeycombs with/without chimney.For honeycombs with the same void volume fraction but different cell shapes,there is little difference on the overall heat transfer rate.To enhance the natural convective heat transfer of honeycombs,these techniques including increasing the length of honeycomb in the streamwise/spanwise direction,increasing the thermal conductivity of hon-eycomb structure or adding a chimney extension may be helpful.
YANG XiaoHuYAN HongBinWANG WenBinJIN LiWenLU TianJianICHIMIYA Koichi
The metal sintering approach offers a costeffective means for the mass-production of open-cell foams from a range of materials, including high-temperature steel alloys, which offer novel mechanical and acoustic properties. In a separate experimental study, the mechanical properties of open-celled steel alloy (FeCrA1Y) foams have been characterized under uniaxial compression and shear loading. Compared to predictions from established models, a significant knockdown in material properties was observed. This knockdown was attributed to the presence of defects throughout the microstructure that result from the unique fabrication process. In the present paper, the microstructure of sintered FeCrA1Y foams was modeled by using a finite element (FE) model. In particular, microstructural variations were introduced to a base lattice, and the effects on the strength and stiffness calculated. A range of defects identified under scanning electronic microscope (SEM) imaging were considered including broken ligaments, thickness variations, and pore blockages, which are the three primary imperfections observed in sintered foams. The corresponding levels of defect present in the material were subsequently input into the FE model, with the resulting predictions correlating well with experimental data.
An effective single layered finite element (FE) computational model is proposed to predict the structural behavior of lightweight sandwich panels having two dimensional (2D) prismatic or three dimensional (3D) truss cores. Three different types of cellular core topology are considered: pyramidal truss core (3D), Kagome truss core (3D) and corrugated core (2D), representing three kinds of material anisotropy: orthotropic, monoclinic and general anisotropic. A homogenization technique is developed to obtain the homogenized macroscopic stiffness properties of the cellular core. In comparison with the results obtained by using detailed FE model, the single layered computational model can give acceptable predictions for both the static and dynamic behaviors of orthotropic truss core sandwich panels. However, for non-orthotropic 3D truss cores, the predictions are not so well. For both static and dynamic behaviors of a 2D corrugated core sandwich panel, the predictions derived by the single layered computational model is generally acceptable when the size of the unit cell varies within a certain range, with the predictions for moderately strong or strong corrugated cores more accurate than those for weak cores.