This paper compared the overall migration of chemicals from PVC film into different food simulants,investigated the change tendency of migration with the time and temperature changed.Migration of chemicals from PVC film into the water food simulants is probably 20mg/dm2and the migration of chemicals from PVC film into the fatty food simulants(Iso-octane)is probably 100mg/dm2.Migration of chemicals from PVC into food simulants become more and more with the extension of time and the increase of temperature until the balanced of migration.