The thermal decomposition of a new antitumor agent, 4-{5-[ 3,4-dimethyl-5-（3,4,5-trimethoxyphenyl）thiophen-2-yl ]-2-methoxyphenyl} morpholine was studied by Differential Scanning Calorimetry （DSC） and Thermogravimetry （TG） / Derivative Thermogravimetry （ DTG ） methods at a flow rate of nitrogen gas of 120 mL/min, The kinetic parameters were obtained from the analysis of the corresponding curves by Kissinger＇s method, Ozawa＇s method and the integral method, The results indicate that the apparent activation energy and pre-exponential constants of the decomposition reaction are 106.67 kJ/mol and 10^6.19s^-1, respectively.
A series of arylsulfonamide and arylamide derivatives have been prepared from anisole in good yields. The structures of those compounds were confirmed by 1H-NMR and MS analysis. Their activities against platelet aggregation were tested in vitro by using the Born test on rabbits.
Poly（propylene fumarate-co-propylene sebacate） （P（PF-co-PS）） was crosslinked with Nvinyl pyrrolidone （N-VP） to form networks. It was investigated as biodegradable bone cement. In this paper, P（PF-co-PS） was synthesized and characterized by ^1H-NMR, FTIR and GPC. The effects of the amount of sebacate segments in P（PF-co-PS） main chains and the quantity of N-vinyl pyrrolidone on the in vitro degradation of the polymer networks were examined. Cylindrical specimens were submerged in phosphate buffered saline （PBS） at 37 ℃ and the pH value of PBS is 7.4 for 10 weeks. The gravimetry and compressive mechanical properties were tested over the degradation period. Networks formed by P（PF-oo-PS）8020/N-VP exhibited higher weight loss and better mechanical properties when compared with poly（propylene fumarate）/N-VP networks. The mechanical properties of P（PF-co-PS）/N-VP can be maintained for a very long time, even for 70 days, the yield strength, fracture strength and compressive modulus are （51.78 ± 2.01） MPa, （52.331 ± 1.84） MPa and （957.78 ± 24.40） MPa, respectively. The results demonstrate that the compressive mechanical properties and degradation velocity can be modulated by the amount of crosslinking agents and sebacate segments along the main chains of copolymers.
