A cross-layer resource allocation scheme based on potential game(CLRA_ PG) is proposed for the downlink multi-cell orthogonal frequency-division multiple-access(OFDMA) system with universal frequency reuse.As a method to mitigate inter-cell interference(ICI),base station coordination has been considered.In the process of the objective function modeling,this paper adopts a pricing mechanism which not only maximizes the individual utility but also considers the interference to other users.Based on the potential game theory,the objective problem is converted to a potential function which can be easily solved.The Karush-Kuhn-Tucker(KKT) conditions and the iterative water-filling algorithm are employed to solve the constraint objective optimization problem.Moreover,extensive simulations are conducted to evaluate how the pricing factors affect the algorithm.At the same time,comparing with the traditional policy,our simulation results show that the proposed scheme can significantly improve the performance of the system.