＜正＞Alkaloids are of biologically significant molecules that are widely investigated in pharmaceutics and medic...
Chun-An Fan State Key Laboratory of Applied Organic Chemistry & College of Chemistry and Chemical Engineering, Lanzhou University,222 Tianshui Nanlu,Lanzhou 730000,CHINA
A proposed strategy for constructing the nine-membered azonane ring system embedded in the isotwistane framework of palhinine A has been preliminarily studied on the basis of an azidoketol fragmentation reaction together with a SmI2-mediated pinacol coupling. Albeit negative results for building the azonane ring scaffold via a tertiary azidoketol fragmentation, the present exploration strategically provided an endeavor to probe the synthetically challenging issue in the synthetic study of palhinine A.
Fang-Xin WangPeng-Lin ZhangHui-Bin WangGuo-Biao ZhangChun-An Fan
