国家自然科学基金(20672077)
- 作品数：1 被引量：1H指数：1
- 相关作者：吴贝杨大成钟裕国沈怡邓勇更多>>
- 相关机构：西南大学四川大学更多>>
- 发文基金：国家自然科学基金更多>>
- 相关领域：化学工程更多>>
- A Novel Enantioselective Synthesis of Linezolid
- ＜正＞Linezolid（Ⅰ） is a oxazolidinone antimicrobial agents developed by Pfizer Company.It was approved by the FDA...
- Hui Zhang Zhipei Sang Zhixiong Huang Yong Deng~* Department of Medicinal Chemistry,West China School of Pharmacy,Sichuan University,Chengdu 610041
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- Synthesis and Biological Evaluation of Novel Non-Peptideαvβ3 Integrin Receptor Antagonists
- Malignant tumor is one of the main diseases that threaten human’s health and life.The metastasis and multidrug...
- Zhixiong Huang XiaodongJing Yong Deng~* Department of Medicinal Chemistry,West China School of Pharmacy,Sichuan University,Chengdu 610041
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- Asymmetric Synthesis of Ramelteon via Desymmetrisation of Meso-3-substituted Glutaric Anhydrides
- ＜正＞Ramelteon is a melatonin receptor agonist with both high affinity for MT1 and MT2 receptors and selectivity...
- Zhipei Sang Jie Wan Mei Li Yong Deng Department of Medicinal Chemistry,West China School of Pharmacy,Sichuan University,Chengdu 610041
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- 5-氨基-1,3-二氢-1,3-二氧-异吲哚-2-丙酸类衍生物的合成及抗血管生成活性研究被引量：1
- 2007年
- 根据RGD序列肽的构效关系,设计并合成了一系列以5-氨基-1,3-二氢-1,3-二氧-异吲哚-2-丙酸为分子骨架的新化合物.其中间体和目标物的化学结构经1HNMR,MS和元素分析确证.体外初步生物活性筛选结果表明,目标物在10-5mol/L浓度下对bFGF诱导的鸡胚绒毛尿囊膜新生血管生成有显著抑制活性.
- 吴贝杨大成沈怡邓勇钟裕国
- 关键词：抗新生血管生成
