Treatment of tetra-iso-butyl-resorcin[4]arene 1 with propargyl bromide in the presence of K2CO3 as base gave an octopus-like octapropargyl tetra-iso-butyl-resorcin[4]arene 2 (C68H72O8, Mr = 1017.26) in a quantitative yield. Single-crystal structure of 2 was determined by X-ray crystallography. 2 crystallizes in the monoclinic system, space group P21/n with a = 13.3247(6), b = 24.7929(11), c = 19.1810(9) ?, β = 109.272(1)o, V = 5981.5(5) ?3, Dc = 1.130 g/cm3, μ = 0.073 mm?1, F(000) = 2176 and Z = 4. Overall structure of 2 reveals an octopus-like resorcinarene with eight propargyl groups in different directions. The resorcinarene adopts the boat conformation where the iso-butyl residues act as four-legged piano stool. The two opposite aryl rings of the macrocyclic framework are almost coplanar, and the two others facing each other are perpendicular to this plane.