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国家自然科学基金(s81071198)

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发文基金:北京市自然科学基金国家自然科学基金更多>>
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Preparation of ^(188)Re-HEDP lyophilized kit for instant bone metastases therapy
2014年
Hydroxyethylidene diphosphonate(HEDP) was prepared and labeled with rhenium-188. Its lyophilized kit was developed for instant preparing of188Re-HEDP.188Re-HEDP showed high focile uptake in normal mice(> 30% ID/g at carrier co-injection) in BABLC/SPF mice. High quality single photon emission computed tomography(SPECT) image of New Zealand rabbit was obtained at 4 h after intravenous injection of 74 MBq radiotracer. The lyophilized HEDP kit affords the new opportunity for routine clinical application in bone metastases therapy.
杨志朱华李囡马云霞张岩
关键词:冻干放射性示踪剂静脉注射
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