A series of 4,6,7,8-tetrahydro-2,5-(1H,3H)-quinolinediones was prepared from ethyl-2-cyanoacetate, aromatic aldehydes and 1,3-cyclohexanedione or 5,5-dimethyl-1,3-cyclohexanedione by two steps, the yields were moderate to excellent. This method is a new practical promising green strategy to synthesize tetrahydronquinolin-2,5-diones.
XIA De-xing FENG Chun WANG Qiu-yan LU Cui-fen CHEN Zu-xing YANG Gui-chun
Task specific onium salt has been presented as soluble support in the synthesis of benzopyrans in this paper. This method allows for results by far superior to those reported other soluble supports and allows for very easy purifications of reaction products.