A new cadmium coordination polymer,[Cd（C14H10N3O5）2（C5H5N）2]n,has been synthesized by the reaction of 2-hydroxy-N＇-（4-nitrobenzoyl）benzohydraizide with cadmium acetate in pyridine and ethanol mixture solution.Its molecular structure was characterized by elemental analysis,IR spectra and X-ray crystal structure determination.Crystal data for this compound：tetragonal,space group I41/a,Mr=871.10,a=16.960（6）,b=16.960（6）,c=28.612（6） ,V= 8230（4）3,Z=8,Dc=1.406 g·m-3 and F（000）=3536.the final R=0.0326,wR=0.0847 for 2682 observed reflections with I 〉 2σ（I） and R=0.0460,wR=0.0896 for all reflections.In the molecular structure of the complex,the cadmium atoms are coordinated to four N and two O atoms forming a slightly distorted octahedral geometry.The intermolecular hydrogen bonds link the neighboring molecules to form a coordination polymer which was then evaluated for its anti-tumor activities against two kinds of cell lines （K562 and BGC） by MTT method.A preliminary bioactivity study indicates that the complex has distinct inhibitory effect on K562 cell lines.
