A theory of a class of higher order singular integral under the operator （L f） （u） =[u1 σf/σu1（u） - u1σf/σu1（u） ＋ f（u）] is given. We transform the higher order singular integral to a usual Cauchy integral, extend the permutation formula of the higher order singular integral deduced by Qian and Zhong in [4] to a general case, and discuss the regularization problem of the higher order singular integral equations with Cauchy kernel and variable coefficients on complex hypersphere.
