A new facile route for preparation of β-TCP/PLLA composites is reported in this letter. SEM images display that β-TCP particles with average diameter of 400 nm were well bonded and distributed within the pore walls of the PLLA scaffolds. The mixture of the novel complex and human dental pulp cells was transplanted subcutaneously into the dorsal surface of a nude mouse. Two months later histological examination showed that new collagen and new dentin formed. The results revealed that the new nano β-TCP/PLLA composite combined with human pulp cells could induce dentin formation, offering a new way to dental tissue engineering.
Feng ZHANGFang MEIXin Zhi WANGXiao Yang HUYong Ming LUOXu Liang DENG
