Title compound has been prepared at room temperature from N-phenylsu-lfonylprolylchloride with n(KCN)/n(CuCN)=1∶1 as catalyst and identified by elemental analysis, IR and MS spectra. The influence of the catalyst constitution on the product distribution has been discussed briefly.
Five new 6-O-prolinated monoacetylbritannilactones have been synthesized from N-acetylprolyl chlorides with 4-N,N-dimethylaminopyridine as catalyst and characterized by elemental analysis, IR, 1H NMR, 1H-1H COSY and MS. The compound 3b displayed a good biological activity for human HL-60 cell in vitro（ED50=4.6 mg/L）.
