Aim Researching the optimal thieshold of image segmentation. M^ethods An adaptiveimages segmentation method based on the entropy of histogram of gray-level picture and genetic. algorithm (GA) was presental. Results In our approach, the segmentation problem was formulated as an optimization problem and the fitness of GA which can efficiently search the segmentation parameter space was regarded as the quality criterion. Conclusion The methodcan be adapted for optimal behold segmentation.