This study aimed to develope the Chinese medicine──Youweikang to treat grastropathy with positive helicobacter pytori. 195 cases gastritis and peptic ulcer demonstrated by gastroscopy, Repid Urease Biopy Test (RUBT) and were treated by Youweikang, using tri-potassiam dicitrato-bismuthate as control. The total effective rate, healing rate of ulcer and the rate of helicobacter pylon elimination between the group of Youweikang and control group is not significant P>0.05). The total markedly effective rate, the elimination rate of the 7 kinds of symptoms in both Youweikang group and control group are respectively 82. 2% and 62.5%, 60.0%and 33. 3%. 84.8% and 56.8%. Youweikang is markedly saperor to control group (P<0.05, 0.01). The animal experiment results show that Youweikang has the fanction of antinflamation,analgesic and can strangthen immunity and increase the activities of pepsase. It is sensitive to helicobacter pylon. Generaly. this study revealed that Youweikang is effective to gostritis and peptic ulcer with positive helicobacter pytori. It can eliminate helicobacter pylon,remit syTnptoms, relief gastritis and spead up ulcer
幽门螺杆菌(Helicobacter Pylordis,HP)是慢性胃炎的病原菌,消化性溃疡和胃癌的高危因素。目前虽已有多种抗生素能清除该菌,但因其副作用及对细菌清除率不高,应用受到限制。本研究选治疗脾胃病常用中药70味,复方汤剂11个,进行体外 HP 杀菌、抑菌系列试验,旨在探讨中药清除 HP 感染的作用和中药对 HP 感染性胃病的治疗方法。