Objective To observe the therapeutic effects on anovulatory infertility with acupuncture and Chinese herbal medicine. Methods Fifty patients with anovulatory infertility were divided randomly into 2 groups with 25 in the observation group and 25 in the control group. Both herbal decoctions and acupuncture treatment were applied to the observation group. For Chinese herbal medicine, according to different phases of menstrual cycle, Cu Luanpao Tang (促卵泡汤 follicle promote decoction), Cu Pailuan Tang (促卵泡汤 ovulation induce decoction) and Cu Huangti Tang (促黄体汤 corpora luteum promote decoction) was given to the patients; and acupoints such as Guanyuan (关元 CV 4), Zhongji ( 中极 CV 3) and LuSnchao Xue(卵巢穴 Extra point) were selected. The control group was asked to take Clomiphene as well as Chorionic Gonadotropin (HCG) injection. Observation is undertaken continuously for 6 cycles, and statistics of ovulation rate and pregnancy rate were collected. Results There were no statistical significance of difference of ovulation rate between the two groups(P〉0.05) ; the pregnancy rate of the observation group is 44. 0%(11/25), which is obviously higher than 16.0% (4/25) of the control group (P〈0.05). Comparison was made on Insler score of the cervical mucus and thickness of the endometrium between the 2 groups, and the result showed that both of the indexes of the observation group were better than those of the control group (P〈0.05, P〈0.01). Conclusion Both of the methods, namely ovulation induction with acupuncture and herbal decoctions and with Clomiphene and HCG injection, are effective for enhancing the ovulation rate, while the former one is better than the later one in the pregnancy rate.