aminophenyl)-2-(1-piperidino)-1-propanone hydrochloride, a sort of water-soluble photoinitiator, was synthesized from acetanilide in three steps, i.e. Friedel-Crafts acylation, α-bromination, amination and hydrochlorination, and its structure was analyzed by IR, MS, UV, elemental analysis, 1H NMR. During the 3rd step, water acted as solvent and piperidine was dripped in at ambient temperature. After reaction at 40 ℃ for 2 h, the mixture was treated with 15%(volume fraction) HCl . The yield was 60.7%. The product has good solubility and photoinitiability. In the air with the distance of 20 cm, the curing time of photosensitive prepolymer was 10s only.
1-（4-Acetylaminophenyl）-α-bromo-1-propanone was synthesized from 1-（4-acetylaminophenyl） propanone through α-hydrogen brominating using Br2 in ethanol as bromination agent,and the yield was 70.4%.The melting point of the target compound was tested and the structure was confirrmed by FT-IR and MS.The route with little pollution and less loss of solvent is practically valuable.
