目的:评价在消毒供应中心护理管理中运用层级管理 + 绩效考核的效果,为该科室护理管理工作提供参考。方法:选择本院消毒供应中心的32名护理人员为研究对象,运用信封法对其分组,其中16例纳入对照组并采取传统护理管理措施,其余16例纳入试验组并采取层级管理 + 绩效考核进行管理,分析各组工作指标合格率、护理人员考核优良率、工作人员压力及应对方式、管理质量、管理效果,研究开展时段为2022年7月~2023年7月。结果:比较两组工作指标合格率,试验组明显更高(P P P P P Objective: To evaluate the effect of using hierarchical management + performance appraisal in the nursing management of disinfectant supply central, and to provide reference for the nursing management of this department. Methods: 32 nursing staff in the disinfection supply central of our hospital were selected as research subjects and grouped by using the envelope method, in which 16 cases were included in the control group and traditional nursing management measures were adopted, and the remaining 16 cases were included in the experimental group and managed by adopting the hierarchical management performance appraisal, and the analysis of the passing rate of the work indexes, the excellent rate of the assessment of the nursing staff, the staff's stress and coping style, the quality of the management, and the management effect of each group was carried out. The study was carried out from July 2022 to July 2023. Results: Comparing the pass rate of work indicators between the two groups, the experimental group was significantly higher (P P P P P < 0.05). Conclusion: The use of hierarchical management performance appraisal in the nursing management of disinfection supply central has a significant effect, can reduce the pressure of staff, so that they can actively deal with the nursing work related to disinfection supply central, can promote the improvement of nursing staff's good rate, improve the qualifi