Copper Salicylate complex was synthesized and its ability that inhibits the reduction of NBT by the superoxide radical(O ·- 2) was measured in aqueous solution and in AOT, TX 100, CTAB lamellar liquid crystals systems. It is obtained that the copper complex had SOD like activity either in solution(ID 50 =1.1×10 -6 mol/L) or in AOT lamellar liquid crystal(ID 50 =2.0×10 -5 mol/L). Experiments show that AOT lamellar liquid crystal had SOD like activity itself. The synergism of copper complex and AOT lamellar liquid crystal can enhance the SOD like activity of the system.