大疱性扁平苔藓(Bullous Lichen Planus, BLP)属扁平苔藓少见型,具体表现为扁平苔藓的典型皮损紫红色丘疹或斑块的基础上出现水疱、大疱亦或是血疱等,目前报道少见。我科于2024年3月收治1例患者,经实验室检查、皮肤病理检查,诊断为大疱性扁平苔藓,予中西医结合治疗。中西医结合治疗后全身皮疹渐平、颜色变暗,水疱消退,瘙痒症状缓解,舌、唇肿胀消失、糜烂面愈合,复查抗BP180抗体转阴,有显著治疗效果,现将病史资料整合并讨论报道如下。Bullous lichen planus (BLP) is a rare type of lichen planus, characterized by typical skin lesions such as purple red papules or plaques, followed by blisters, bullae, or blood blisters. Currently, reports on BLP are rare. Our department admitted one patient in March 2024. After laboratory examination and skin pathological examination, it was diagnosed as bullous lichen planus and treated with a combination of traditional Chinese and Western medicine. After the combination of traditional Chinese and Western medicine treatment, the rash on the whole body gradually flattened, the color became darker, the blisters disappeared, the itching symptoms were relieved, the swelling on the tongue and lips disappeared, and the eroded surface healed. The anti-BP180 antibody turned negative after re-examination, and there was a significant therapeutic effect. The medical history data is now integrated and discussed as follows.
