带状疱疹后神经痛(PHN)是带状疱疹皮损愈合后在原发病部位出现超过1个月持续的疼痛,为带状疱疹(HZ)最常见的并发症,其发病特点是持续性疼痛部位为受损神经支配区域。西医治疗带状疱疹后神经痛的原则主要是控制疼痛和营养神经,具有一定的局限性;虫类药物是中医药的重要组成部分,多具有活血化瘀、通络止痛等功效,现代药理学研究证明,虫类药物能够缓解带状疱疹带来的疼痛并改善疾病症状,本文从虫类药物治疗带状疱疹后神经痛的中医药理论和现代药理学研究出发,探索其在带状疱疹后神经痛中的应用,以期推动相关领域的基础和临床研究发展,为带状疱疹的诊疗提供支持和参考。Postherpetic neuralgia (PHN) is a persistent pain that lasts more than one month after the healing of herpes zoster skin lesions in the original affected area, which is the most common complication of herpes zoster (HZ) and its characteristic feature is persistent pain in the area of damaged nerve supply. The principle of Western medicine treatment for PHN is mainly to control pain and nourish nerves, which has certain limitations. Insect drugs are an important part of traditional Chinese medicine and are often used to promote blood circulation, remove blood stasis, and relieve pain. Modern pharmacology has shown that insect drugs can relieve pain caused by herpes zoster and improve disease symptoms. This article explores the application of insect drugs in the treatment of postherpetic neuralgia from the perspective of traditional Chinese medicine theory and modern pharmacology, with the aim of promoting the development of related basic and clinical research and providing support and reference for the diagnosis and treatment of herpes zoster.
