[Objective] The aim was to explore living conditions of Bellamya sp. in polluted water with aquatic vegetation in different varieties. [Method] With wetland in winter simulated, effects of polluted water on SOD, MDA and survival rate of Bellamya sp. were researched to further study living condition of Bellamya sp. in wetlands at scale with aquatic vegetation. [Result] According to simulation, Altemanthera philoxeroides was highest in survival rate and Wolffia arrhiza was the lowest; SOD activity of Bellamya sp. changed from decreasing to increasing; MDA activities changed from increasing to decreasing in groups of Wolffia arrhiza, Salix saposhnikovii and control group and changed little in group of Ceratophyllum demersum and Alternanthera philoxeroides. The changes of MDA in group of Oenanthe stolonifer proved much more complicated. [Conclusion] Of the aquatic environment with five varieties of aquatic vegetation, combined group of Alternanthera philoxeroides and Bellamya sp. was of significant resistance against eutrophication, and the group of Wolffia arrhiza and Bellamya sp. proved with poorest in resistance.