Objec ve To observe the effi cacy of electroacupuncture on glycometabolism disturbance in metabolism syndrome. Methods With matched-pairs design,80 pa ents mee ng with the diagnos c criteria for glycometabolism abnormali es were randomized into the group combining acupuncture and medica on(group A) and the western medicine group(group B),and 40 pa ents were included in each group. Electroacupuncture was carried out on back-shu points,Zúsānlǐ(足三里 ST 36),Zhōngwǎn(中脘 CV 12),Sānyīnjiāo(三阴交 SP 6) and other acupoints for group A,needles were retained for 20 min except back-shu points,once a day,con nuous ten mes as a treatment course,the next treatment course was started a er an interval for 3–5 days,and totally 3 treatment courses were carried out; furthermore,the pa ents were orally administered with Glucotrol XL and felodipine,5 mg each,once a day. The pa ents in group B were treated simply with drugs(the medica on was the same to that for the group A). Body mass index(BMI),related biochemical indices and blood pressure of the pa ents were measured before and a er the interven on,respec vely. Results BMI,blood-fas ng glucose,blood glucose 2 h after meal,fasting insulin,insulin resistance index,systolic pressure and diastolic pressure in group A all significantly improved in comparison to those before the electroacupuncture intervention(P0.01). The difference in BMI in group B before and after the treatments was not statistically significant(P0.05),and other indices all showed significant improvements(P0.01). The improvements in the indices as mentioned above in the group A after treatment were significantly better than those in the group B(P0.01). Conclusion Electroacupuncture intervention can significantly reduce weight,combina on of acupuncture and medica on shows be er effi cacy in reducing blood glucose,improving insulin sensi vity and insulin resistance in comparison to simple administra on with medica ons.