Objective To compare the difference in the therapeutic effects on diarrhea- type irritable bowel syndrome （D-IBS） between acupuncture based on soothing the liver and strengthening the spleen and western medicine. Methods Seventy cases were randomized into an acupuncture group and a western medicine group, 35 cases in each one. In the acupuncture group, the conventional acupuncture was applied at Tianshu {天枢 ST 25）, Zusanli （足三里 ST 36）, Shangjuxu {上巨虚 ST 37）, Sanyinjiao （三阴交 SP 6）, Taichong （太冲 LR 3） and so on. Electric stimulation was supplemented at bilateral ST 25. The treatment was given once a day, 3-4 treatments in a week. In the western medicine group, pinaverium bromide （dicetel） was prescribed for oral administration, 50 mg each time, three times a day. Four weeks made one session in the two groups. Separately, before treatment and after 1 session treatment, the integral of clinical symptom and the score in the scale of the quality of life measure for irritable bowel syndrome （IBS-Q OL） were observed for the patients in the two groups. The efficacy and recurrence rate were assessed in the two groups. Results The symptom integral and IBS-QOL score in the two groups were improved significantly after treatment Call P〈0.01）, and the improvements in the acupuncture group were superior to that in the western medicine group （P〈0.01）. The effective rate was 94.3% {33/35） in the acupuncture group, which was superior to 77.1% （27/35） in the western medicine group （P〈0.01）. In 3 months, the recurrence rate was 36.4% （12/33） in the acupuncture group, which was lower apparently than 72.0% （18/25） in the western medicine group （P〈O.01）. Conclusion Acupuncture therapy based on soothing the liver and strengthening the spleen achieves the superior efficacy on D-IBS as compared with western medication, pinaverium bromide. This therapy improves apparently the quality of life of the patients and is lower in recurrence rate.
目的:运用数据挖掘技术探讨针灸治疗肠易激综合征(IBS)的选穴规律。方法:计算机检索中国期刊全文数据库(CNKI)、万方学术期刊全文数据库(WanFang Data)、维普中文科技期刊数据库(VIP)、PubMed、web of science等数据库中针灸治疗IBS的临床文献,筛选文献并提取腧穴处方,运用软件分析取穴规律。结果:描述性分析提示,针灸治疗IBS最常选取的经脉分别是足阳明胃经、足太阳膀胱经和任脉;主要选取募穴、下合穴、五输穴等特定穴,腧穴部位分布以四肢和胸腹为主。关联规则分析得出针灸治疗肠易激综合征的核心穴对为“天枢-足三里”,核心腧穴处方为“天枢、足三里、上巨虚”。结论:通过数据挖掘技术,探索针灸治疗肠易激综合征的取穴规律,为临床针灸治疗肠易激综合征提供科学依据。
