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全麻开胸手术前静注氯胺酮对术后痛的影响被引量:1
2001年
目的 :观察开胸手术切皮前静注氯胺酮对术后痛的影响。方法 :36例ASAⅠ~Ⅱ级食管癌择期手术患者 ,随机分成两组 ,K组为氯胺酮组 ,C组为对照组。术前不用阿片类药物。麻醉诱导静注异丙酚 (2mg/kg)、司可林 (1~ 1.5mg/kg) ,气管插管机械通气。K组于切皮前 10分钟静注氯胺酮 1mg/kg(5ml溶液 ) ,C组切皮前 10分钟静注生理盐水 5ml。术中静滴异丙酚和吸入安氟醚维持麻醉 ,间断静注维库溴铵保持肌松。术后患者完全清醒后拔除气管导管送回病房。采用VAS法评价术后疼痛 ,当VAS≥ 6分时 ,给患者肌注杜冷丁 5 0mg。比较两组术后 0~ 4h、4~ 8h、8~ 12h、12~ 16h、16~ 2 0h、2 0~ 2 4h各时段肌注度冷丁人数及度冷丁平均用量。结果 :K组前 16h各时段肌注度冷丁人数显著少于C组 (P 0 .0 5 )。K组术后 2 4h度冷丁平均用量显著少于C组 (P 0 .0 5 ) ,但主要集中在前 16小时各时段 ,其后各时段两组无显著差异。结论 :开胸手术切皮前静注氯胺酮能显著降低术后痛。
唐育民魏湘华郝冰
关键词:开胸手术氯胺酮静脉注射
针麻开胸手术超前镇痛作用临床观察被引量:3
2001年
Objective: To observe the effect of preemptive analgesia of electroacupuncture(EA) for patients undergoing thoracic operation. Methods: 54 adult ASA (American Standards for Assessing the State of the Patient of American Anesthesia Association) grade Ⅰ and Ⅱ patients undergoing thoracic operation were randomly divided into three groups. The single blind method was used in the study. Patients in group A (n=18) were given with EA by using Han’s Acupoint Nerve Stimulator(HANS) for stimulating Xiayifeng point and Sanyangluo (SJ 8) to Ximen (PC 4; 2/15Hz, 2~4 mA and 15~ 20 min) first, then given with inhalational anesthetic (enflurane) and intravenous administration of fentany 2 μg/kg/hr, vecuronium 0.12 mg/kg/0.5 hr and propofol 2 mg/kg, During operation, HANS stimulation was given continuously, and combined with vecuronium 0.12 mg/kg. In group B (n=18), acupoint surface electrical stimulation (without acupuncture) combined with anesthetics (being same to those of group A) was given. In group C (n=18), only anesthetics were used. Then, the number of patients needing intramuscular injection of dolantin and the average doses in 3 groups were observed at 0~4 hr, 4~8 hr, 8~12 hr, 12~16 hr, 16~20 hr and 20~24 hr after operation. Results: The average dose of the injected dolantin in Group C was significantly higher than those of group A and B(P<0.001). 0~4 hr, 4~8 hr, 8~12 hr, 12~16 hr and 16~20 hr after operation, the number of patients needing intramuscular injection of dolantin in group A, B and C were 2, 2 and 9; 1, 2 and 7; 1, 2 and 6; and 1, 3 and 6 respectively. It is clear that the number of patients needing dolantin of group C is evidently more than those of group A and B (P<0.05). Conclusion: Acupuncture stimulation conducted before thoracotomy has a preemptive analgesia effect.
唐育民魏湘华尹志礼郝冰
关键词:针刺麻醉胸部超前镇痛
电针对安氟醚最低肺泡有效浓度的影响
2001年
Objective: To study the effect of electroacupuncture on minimal alveolar concentration (MAC) of enflurane. Methods: Fifty adult ASA grade Ⅰ~Ⅱ patients undergoing abdominal operation were randomly divided into group A (n=25, enhalating enflurane alone) and group B (n=25, enhalating enflurane plus electroacupuncture). MAC was determined according to Egger’s method. Xiayifeng point and Sanyangluo (SJ 8) were punctured and stimulated with HANS (2/15 Hz, 2~4 mA, sparse dense waves, 15~20 min). Results: The MAC of group A was 1.67 Vol% and that group B was 1.15 Vol%. The difference between two groups was very significant(P<0.01). Conclusion: Acupuncture combined with enhalation of enflurane anesthesia for abdominal operation can effectively lower the minimal alveolar concentration of enflurane.
唐育民魏湘华尹志礼郝冰
关键词:电针安氟醚最低肺泡有效浓度腹部外科手术针刺麻醉
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