Quantitative determination of QT341 in human plasma was explored by mass spectrometry.API 3000 LC-MS/MS were used in this study.The established method proved to be fast and specific.Some ideas about the quantitative analysis of the drug in the treatment of ischemic heart disease and the method for the solid-phase extraction from the human plasma were introduced in this paper.
HPLC-MS/MS methods were developed to determine 19 kinds of free amino acids in human serum. API 4000 and Quattro Ultima HPLC-MS/MS systems were used in this study. The established method proved to be fast and specific.It can be applied to determine 19 kinds of amino acids simultaneously and also can be used in the disease screening studies associated with amino acids disorders.
