To observe the effect of herb separated moxibustion on the expression of IL 1β and TNF α in ulcerative colitis rats. METHODS After establishment of model of ulcerative colitis. Rats were randomly divided int five groups:Herb Separated Moxibustion group (HSM=9), Electropuncture group (EP=9), Warming Moxibustion group (WM=9), Model Control group (MC=10) and Normal Control group (NC=8). After treatment, all rats in each group were killed for examination. RESULTS There was no or a few IL 1β and TNF α positive cells in the colonic mucosa of NC rats,while it was significantly expressed in that of MC rarts. IL 1β and TNF α positive cells were markedly lower in WG than that in MC rats. It was much more lower in EP and HSM rats.CONCLUSION Herb separated moxibustion greatly inhibited the expression of IL 1β and TNF α in ulcerative colitis rats. It leads to reducing inflammation in colonic mucosa.
